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Identical to us, generally our skin-care elements work higher in pairs. The symbiotic relationship between these dynamic duos permits them to work even higher collectively than they’d on their very own. “As a dermatologist, I often advocate combining particular skin-care elements to maximise their advantages and handle a wide range of pores and skin considerations,” says New York dermatologist Elaine Kung, MD. “These synergistic, strategic pairings can create a stronger and well-rounded strategy to reaching your required outcomes.”
Vitamin C + Vitamin E
These two antioxidants work in tandem to advertise a more healthy complexion. “Vitamin C helps brighten pores and skin and promote collagen, and vitamin E helps forestall injury from free radicals,” Melville, NY dermatologist Kally Papantoniou, MD says. This mixture was largely popularized by SkinCeuticals’ C E Ferulic serum ($182), notes Fort Lauderdale, FL dermatologist Dr. Matthew Elias, who explains that though vitamin C has many advantages, it has issue being absorbed by the pores and skin. The pair is “extra steady together,” provides Greenwich, CT dermatologist Lynne Haven, MD. Combining vitamin C with different antioxidants enhances its supply to the pores and skin, main to raised outcomes, and vitamin E additionally helps forestall the oxidation of vitamin C.
Nutritional vitamins C + E suggestions: SkinMedica Vitamin C + E Complicated ($106), Paula’s Selection C15 Tremendous Booster ($55), Maelove Glow Maker Vitamin C Serum ($33)

Saliclyic Acid + Niacinamide
Based on Dr. Elias, niacinamide pairs properly with virtually something in your skin-care routine. “Niacinamide boasts soothing properties that may assist calm any irritation attributable to betahydroxy acids (like salicylic acid), that are notably efficient for minimizing breakouts,” making this mixture splendid for these with acne-prone pores and skin who wrestle with irritation from conventional zits remedies.
Davie, FL dermatologist Mariana Blyumin-Karasik, MD says salicylic acid and niacinamide particularly have “a successful synergy for breakouts and blemish-prone pores and skin.” Salicylic acid is a betahydroxy acid derived from willow bark that helps unclog pores. Nevertheless, Dr. Blyumin-Karasik notes that as a result of it has an acidic pH, it may be a bit drying, and pH-neutral niacinamide is the proper ingredient to steadiness it out. “Each of those elements work effectively to cut back oil manufacturing and irritation within the pores and skin, and have average antibacterial properties and brightening results,” she provides. “Therefore, clear pores and skin tango is achieved with the assistance of this duo.”
Salicylic acid suggestions: La Roche-Posay Effaclar Salicylic Acid Pimples Therapy Serum ($40) & The Abnormal Salicylic Acid 2% Resolution ($7)
Niacinamide suggestions: Dieux Deliverance Antioxidant & Niacinamide Serum for Calm & Even Pores and skin ($69) & Dr. Sturm The Higher B Niacinamide Serum ($60)

Hyaluronic Acid + Ceramides
Hyaluronic acid and ceramides are a match made in hydration heaven. Ceramides assist shield the pores and skin barrier and retain moisture ranges, whereas hyaluronic acid helps hydrate the pores and skin straight by attracting water, Dr. Papantoniou says. “These elements mix effectively collectively as a result of they’re cousins of varied pores and skin hydrators, starting from light-weight water-soluble hyaluronic acid to a average thickness, oil-based emollient reminiscent of ceramides,” explains Dr. Blyumin-Karasik.
Hyaluronic acid + ceramides suggestions: CeraVe Hydrating Hyaluronic Acid Face Serum ($26), Paula’s Selection CALM Repairing Serum ($44), VANICREAM Every day Facial Moisturizer ($19)

Glycerin + Hyaluronic Acid
A molecule that may maintain 1,000 occasions its weight in water, hyaluronic acid “hydrates pores and skin and may penetrate its superficial layers to easy the looks of traces,” says Dr. Papantoniou. Glycerin is on double obligation, serving to to draw water to hydrate the pores and skin after which retain the moisture. “Collectively, these elements decelerate water evaporation and promote pores and skin water retention and the gradual shedding of useless pores and skin cells on the floor,” explains Dr. Blyumin-Karasik. “Total, this results in plumper and smoother-looking pores and skin.”
Glycerin + hyaluronic acid suggestions: Olay Hyaluronic + Peptide 24 Serum ($30), Summer season Fridays Dream Oasis Deep Hydration Serum ($44), Tatcha The Dewy Serum ($89)

Retinoids + Benzoyl Peroxide
Retinoids have seemingly limitless advantages, together with lowering wrinkles and hyperpigmentation. Certainly one of their most beloved perks is their skill to struggle zits, and when paired with benzoyl peroxide, the duo doubles down on breakouts. Retinoids
exfoliate the pores and skin and decrease oil manufacturing, which may help cut back zits flare-ups. “Benzoyl peroxide helps cut back bacterial progress, and when paired with retinoids, this works effectively for zits.” Nevertheless, Dr. Elias warns towards mixing these two elements by yourself, as a result of “they’ll cancel one another out and result in zero efficacy. That being stated, there are actually some steady prescription merchandise that mix a retinoid and benzoyl peroxide.” In case you’re keen on utilizing considered one of these merchandise “to supercharge your zits treatment,” Dr. Elias advises speaking to a board-certified dermatologist.
Based on beauty chemists Victoria Fu and Gloria Lu, there’s really fairly a bit of information displaying how the mixture of adapalene, a topical retinoid, and benzoyl peroxide results in higher advantages in tackling zits breakouts and stopping zits scarring versus utilizing simply one of many elements by itself.
Retinoids + benzoyl peroxide suggestions: Twyneo & Epiduo
Glycolic Acid + Retinoids
Retinoids are already extremely efficacious on their very own, however glycolic acid is usually a great addition for the lively ingredient. “Glycolic acid helps exfoliate, and the retinoids assist promote wholesome pores and skin maturation and exfoliation, cut back oil manufacturing, and enhance collagen manufacturing,” says Dr. Papantoniou. “Collectively, the 2 potentiate one another, additional serving to to fade discoloration and the looks of advantageous traces.” However, as a result of each elements may be irritating, it’s necessary to ease in. Keep away from utilizing glycolic acid and retinol at the very same time, and quite incorporate them as soon as per week every, slowly working your approach as much as alternating them nightly in case your pores and skin can tolerate it.
Glycolic acid suggestions: SkinCeuticals Glycolic 10 Renew In a single day ($90) & The INKEY Record Glycolic Acid Toner ($14)
Retinoid suggestions: SkinBetter Science AlphaRet In a single day Cream ($135) & Altreno

Tiger Grass + Aloe Vera
Tiger grass goes by many names, together with cica and gotu kola. No matter you name it, it’s well-known for shade correcting and
lowering irritation, making it nice for these with delicate, irritated pores and skin, together with rosacea or sunburn. Pairing tiger grass with aloe vera simply is sensible, as they’ve related advantages. Dr. Blyumin-Karasik says, “Each botanicals have unimaginable anti-inflammatory and pores and skin barrier–restore properties, which makes them important for calming and therapeutic reactive or irritated pores and skin.”
Tiger grass + aloe vera suggestions: Herbivore Inexperienced Magic ($48) & ELEMIS Superfood Cica Calm Hydration Juice ($54)

Niacinamide + Retinoids
Retinol may be irritating, particularly for rookies or these with delicate pores and skin, so pairing it with any product that may assist fight undesirable unwanted side effects is good. Fu and Lu say niacinamide is as much as the duty of lowering the depth of irritation that may include utilizing retinol. In the meantime, niacinamide doubles down on the advantages of retinol. “Niacinamide can even work to brighten, even pores and skin tone from a special organic pathway than retinol. One other strong pairing!”
Niacinamide + retinoid suggestions: La Roche-Posay Retinol B3 Serum ($45), Youth To The Individuals Retinal + Niacinamide Youth Serum ($72), L’Oréal Revitalift Pressed Night time Moisturizer with Retinol ($40)

Vitamin C + Sunscreen
Sunscreen is vital to maintain pores and skin protected each day and vitamin C is essential to assist forestall and reverse any injury that does break via, so why not use each? Beauty chemist Ron Robinson says this pair works “very effectively collectively as a result of collectively they supply extra complete safety towards damaging UV rays in addition to free radicals.” You could find these elements mixed in his model’s BeautyStat Common C Pores and skin Refiner SPF 50 ($85).
Vitamin C + sunscreen suggestions: Murad Important-C Day Moisture Broad Spectrum SPF 30 ($69), SkinCeuticals Every day Brightening UV Protection Sunscreen SPF 30 ($60), Shiseido City Atmosphere Vita-Clear SPF 42 Face Sunscreen with Vitamin C ($38)

Niacinamide and Ceramides
This skin-soothing duo is right here to place out any fires. “Niacinamide strengthens the pores and skin barrier, whereas ceramides are pure lipids that assist retain moisture and shield delicate pores and skin from environmental irritants,” says Dr. Kung. “Collectively, they create a protecting protect, mitigating sensitivity and selling total pores and skin well being.”
Niacinamide + ceramides suggestions: Skinfix Barrier+ Triple Lipid + Collagen + Niacinamide Activating Serum ($69), CeraVe Facial Moisturizing Lotion PM ($20), Nécessaire The Physique Cream ($48)

Ascorbic acid + Tiger Grass
This pairing of ascorbic acid, a type of vitamin C, and tiger grass has been pinpointed as a duo that promotes some severe outcomes. Based on the chemists, “This pairing was discovered to have some nice wrinkle discount advantages even on the decrease focus of 5 p.c ascorbic acid.”
Ascorbic acid suggestions: Vichy LiftActiv Brightening and Anti-Getting older Vitamin C Serum ($35) & Dr. Dennis Gross Vitamin C Lactic Acid Firming Serum ($115)
Tiger grass suggestions: Dr. Jart+ Cicapair Delicate Pores and skin Serum for Redness and Barrier Restore ($54) & Centella Delicate Cica-Cream ($46)

Retinol + Hyaluronic Acid
“Whereas retinol is a gold commonplace for exciting collagen manufacturing and lowering wrinkles, it may generally result in dryness,” notes Dr. Kung. Introducing hyaluronic acid, a humectant, helps draw moisture and plump pores and skin to cut back advantageous traces and wrinkles whereas additionally making retinol much less irritating, she explains.
Retinol + hyaluronic acid suggestions: ROC Derm Correxion Fill + Deal with Serum ($39), Paula’s Selection RESIST Intensive Restore Cream ($38), Elizabeth Arden Retinol + HPR Ceramide Fast Pores and skin-Renewing Water Cream ($92)

Peptides + Retinoids
Dr. Kung says peptides and retinol are “a dynamic duo for firmer and younger-appearing pores and skin, and who doesn’t need that? On this mixture, “the retinol works on a mobile degree to spice up collagen manufacturing, whereas peptides are the constructing blocks for collagen,” she explains.
Peptides + retinoid suggestions: Allies of Pores and skin Retinal & Peptides Restore Night time Cream ($121), iNNBEAUTY PROJECT Retinol Remix ($48), Kiehl’s Micro-Dose Anti-Getting older Retinol Serum ($65)

Tiger Grass + Hyaluronic Acid
This pair is ideal for these with dry, delicate pores and skin. By itself, tiger grass has calming and therapeutic properties, splendid for soothing irritation on delicate pores and skin, says Dr. Kung. Including hyaluronic acid to the combination “offers much-needed hydration, additional selling a wholesome and comfy complexion.”
Tiger grass suggestions: Laneige Cica Sleeping Masks ($34) & Mango Individuals Juicy Glow Prep & Hydrate Balm Stick ($30)
Hyaluronic acid suggestions: Alastin Skincare Hyaluronic Acid Immerse Serum ($118) & Peter Thomas Roth Water Drench Hyaluronic Cloud Serum ($68)

Hyaluronic Acid + PolyGlutamic Acid
This duo is tremendous hydrating. Hyaluronic acid has a stellar popularity, however in case you’re unfamiliar with PolyGlutamic Acid it’s price noting it may maintain as much as 4000 occasions its weight in water. Each elements are humectants that entice and bind water to the pores and skin, says Robinson. An authority-mixed system of those two and lots of extra wonderful elements may be discovered within the new BeautyStat Peptide Wrinkle Enjoyable Moisturizer ($72).
Hyaluronic acid suggestions: Eminence Strawberry Rhubarb Hyaluronic Serum ($55) & Caudalie Vinosource-Hydra S.O.S. Serum ($43)
PolyGlutamic acid suggestions: Contemporary Lotus Youth Protect Radiance Renewal Night time Cream ($58) & The INKEY Record Polyglutamic Acid Serum ($15)

Vitamin C + Hyaluronic Acid
We love the brightening, free-radical combating vitamin C. By holding your pores and skin hydrated, with one thing like hyaluronic acid, you’ll have “a extra optimum surroundings for vitamin C to work its magic, leading to a brighter and extra even complexion,” says Dr. Kung.
Vitamin C + hyaluronic acid suggestions: iS Medical Tremendous Serum Advance Plus ($158), Dermalogica Biolumin-C Vitamin C Gel Moisturizer ($69), PCA Pores and skin C-Quench Antioxidant Serum ($130)

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